Reishi - Ganoderma Lucidum
- eshed haklai
- Oct 10, 2025
- 2 min read
Updated: Dec 28, 2025
The Reishi mushroom, also known as Lingzhi in China and the “Mushroom of 10,000 Years” (Manentaka) in Japan, is considered one of the most important mushrooms in traditional East Asian medicine. Its diverse uses and medicinal potential have made it one of the most researched mushrooms worldwide.
Reishi is a hard wood mushroom with a shiny red-brown cap and a woody texture. It is primarily found in tropical and humid climates, especially in China, Japan, and Southeast Asia. Due to its bitter taste and tough texture, it is rarely eaten fresh; instead, it is typically dried and boiled to prepare teas or extracts.

Chemical Properties: Like other medicinal mushrooms, Reishi contains polysaccharides from the beta-glucan family (β-Glucans), which have immunomodulatory effects.
It also contains triterpenoids, such as ganoderic acids, with anti-inflammatory and antioxidant activity.
Proteins and peptides, such as Ling Zhi-8, exhibit immunological activity. Sterols include ganoderol, ganoderic acid, ganodernol, ganodermantriol, lucidial, and ganodermadiol.
Traditional Medicine:
In China, traditional use of Reishi dates back 2,000–2,500 years. It is mentioned in ancient texts like the Shen Nong Ben Cao Jing (1st–3rd centuries CE), where it is described as the “mushroom of immortality” associated with longevity, immune support, and overall health. Traditional Chinese medicine uses include:
Enhancing immune system function
Reducing fatigue and improving mood
Supporting cardiovascular health
Regulating blood sugar levels
In Japan, the “Mushroom of 10,000 Years” has been used to improve overall health, boost energy, and enhance vitality, with documentation dating back to the feudal period (8th–12th centuries).
Medicinal Properties – Scientific Highlights:
Immune Support: Beta-glucans in Reishi enhance the activity of white blood cells, T cells, and NK cells, strengthening the immune system.
Anti-inflammatory and Antioxidant Activity: Reishi triterpenoids and polysaccharides have antioxidant properties and modulate inflammation, supporting cellular and tissue health.
Anticancer Properties: In vitro and animal studies indicate Reishi may inhibit cancer cell growth and reduce metastasis.
Cardiovascular Health: Research shows Reishi can improve lipid profiles, lower blood pressure, and support blood sugar management.
Fatigue and Mood: Reishi supplementation has been shown to reduce fatigue and depression, especially in individuals with chronic illnesses.
Kidney Health: Evidence suggests Reishi may protect the kidneys, including against damage caused by chemotherapy.
Reishi also exhibits many additional health benefits not covered here: it is anti-allergic, supports anxiety management, improves liver function, positively influences the gut microbiome, protects the nervous system, and more.
For a detailed article on Reishi and neurodegenerative diseases, click here.
Side Effects and Precautions:
Reishi is generally considered safe, but caution is advised in the following cases:
Anticoagulant medication
Pregnancy and breastfeeding
Mushroom allergy
It is recommended to consult a physician or qualified practitioner before starting Reishi, especially at high doses or when combined with other medications.
For further questions, please contact us and provide details of your inquiry.



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